The Project

The issue

Pelvic prolapse is usually due to age and multiple pregnancies that affect women's health by damaging pelvic muscles in the pelvis. In these particular conditions, the abdominal organs are no longer held and can then descend through the genital tract, causing genital prolapse.

Surgical management of this problem is becoming more and more frequent, but current solutions are inadequate. Indeed, the existing systems currently in place are poorly adapted and too rigid. These implants are derived from those used in visceral surgery (hernia) and have not been specifically developed, particularly with regard to their mechanical properties. As a result, many patients experience failure and recurrence, as well as feelings of irritation and discomfort.

The treatment of genital prolapse therefore remains a health issue, in particular because of problems of tolerance of existing devices due in particular to the inadequacy of the mechanical behaviour of the reinforcements in relation to the mechanical behaviour of surrounding living tissues.

The Probiomesh Project

The Probiomesh project aims to improve surgical management of genital prolapse.

This improvement is envisaged through the creation of new textile implants. These new implants will be semi-resorbable and will have mechanical properties perfectly adapted to the problem of genital prolapse.
To achieve these objectives, various transversal and cross-border actors have come together. These actors are the Centre Hospitalier Régional Universitaire de Lille, the Ecole Centrale Lille, MateriaNova and Centexbel. Between the four of them, these actors cover all the fields of expertise (medical sciences, polymers and textile processes) necessary for the success of this project.

The great strength of this association, in addition to the various complementary skills of the partners, also lies in its cross-border nature. Indeed, thanks to it, actors from different horizons will have the opportunity to meet, discuss and open new therapeutic paths. In addition, the results will benefit a greater number of practitioners and a greater number of patients.